One prescription medicine used to treat moderate to moderately severe pain is called tramadol, which is categorized as an opioid analgesic. By preventing pain signals from entering the brain and altering our perception of pain, it affects the central nervous system. This centrally active medication modifies the brain's mu-opioid receptors, which in turn modifies the perception of pain signals. Tramadol also enhances its ability to relieve pain by blocking the reuptake of neurotransmitters such as norepinephrine and serotonin.
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