With regard to the illicit marketing of potentially harmful, unapproved, and misbranded versions of opioid pharmaceuticals, such as tramadol and oxycodone, nine online networks operating a total of 53 websites have been cautioned by the U.S. Food and Drug Administration to cease their activities. Businesses that disregard the warning letters' instructions and don't pay up could face injunctions or product seizures, among other forms of enforcement action.
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