Synthetic opioid analgesics, such as tramadol, are useful in treating moderate- to severe-level pain. Pain can be reduced by altering the way the brain responds to pain signals, which in turn affects the CNS. Tramadol is often used after other painkillers or nonsteroidal anti-inflammatory drugs (NSAIDs) have been tried. This drug's dual mode of action involves binding to opioid receptors and preventing the absorption of neurotransmitters like norepinephrine and serotonin that are important in pain regulation. Because of this, Tramadol is a great medicine for treating both acute and chronic pain.
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