Category II substances include semi-synthetic opioid painkillers like hydrocodone. The US Food and Drug Administration (FDA) has approved this drug for use in pain relief. Severe chronic pain that cannot be effectively treated with nonopioid therapies and necessitates opioid analgesia is the main indication for using hydrocodone. Because combination hydrocodone formulations have antitussive characteristics, they are utilized to treat nonproductive coughs.
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